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This sequence adjust has an effect on codon 777 on the GAA mRNA. It's a 'silent' change, indicating that it does not alter the encoded amino acid sequence in the GAA protein. This variant also falls at the last nucleotide of exon sixteen, which can be Section of the consensus splice internet site for this exon. This variant is current in populace databases (rs375311693, gnomAD 0.03%). This variant has not been claimed during the literature in persons impacted with GAA-similar situations.
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This value is calculated by NCBI according to information from submitters. Read our principles for calculating the critique position. The quantity of submissions which lead to this overview standing is proven in parentheses.
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When the group requests your account facts, be mindful to give them correct data. Just after this, a link to reset your password will likely be despatched to you thru electronic mail.
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